Journal article

The use of a risk assessment and decision support tool (CRISP) compared with usual care in general practice to increase risk-stratified colorectal cancer screening: Study protocol for a randomised controlled trial

JG Walker, F Macrae, I Winship, J Oberoi, S Saya, S Milton, A Bickerstaffe, JG Dowty, R De Abreu Lourenço, M Clark, L Galloway, G Fishman, FM Walter, L Flander, P Chondros, D Ait Ouakrim, M Pirotta, L Trevena, MA Jenkins, JD Emery

Trials | BMC | Published : 2018

Abstract

Background: Australia and New Zealand have the highest incidence rates of colorectal cancer worldwide. In Australia there is significant unwarranted variation in colorectal cancer screening due to low uptake of the immunochemical faecal occult blood test, poor identification of individuals at increased risk of colorectal cancer, and over-referral of individuals at average risk for colonoscopy. Our pre-trial research has developed a novel Colorectal cancer RISk Prediction (CRISP) tool, which could be used to implement precision screening in primary care. This paper describes the protocol for a phase II multi-site individually randomised controlled trial of the CRISP tool in primary care. Meth..

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Grants

Awarded by National Science Foundation


Funding Acknowledgements

This work is funded by a National Health and Medical Research Council (NHMRC, Canberra, ACT, Australia) Centre of Research Excellence grant (APP1042021), NHMRC project grant (APP1121104) and Victorian Cancer Agency (Melbourne, VIC, Australia) grant (HSR15019). MP is supported by an NHMRC Career Development Fellowship. JDE is supported by an NHMRC Practitioner Fellowship. FMW is supported by a NIHR Clinician Scientist award (UK). MAJ is supported by an NHMRC Senior Research Fellowship. SS is a PhD candidate supported by an Australian Government Research Training Program Scholarship.